Toll-like receptors and their dual role in periodontitis: a review.

The Role of Toll-Like Receptors in Breast Cancer

Breast cancer is highly prevalent worldwide. Treatment of this disease is a major global public health problem; therefore, numerous studies have explored new molecular profile helping for breast cancer therapy. Different risk factors are attributed to breast cancer; however, chronic inflammation and immune regulation are highly essential. Various molecules impact this context, including toll-li...

The Role of Toll Like Receptors in Pregnancy

The Efficacy of Toll-Like Receptors in Awakening Dendritic Cell/Natural Killer Cell System for Eradication of Tumors

Natural killer (NK) cells are effector cells of the innate immune system that exert direct cytotoxic functions. Ubiquitously-expressed toll-like receptors (TLRs) have been recognized as one of the major components promoting dendritic cell (DC) maturation, which may induce polarized immune responses beneficial to cancer immunotherapy. TLR-activated NK cells and DCs are prerequisite for robust ac...

P-184: The Role of Cell Surface Toll Like Receptors in Endometriosis

Background: Toll like receptors (TLRs) are a major family of innate immune systems which recognize specific pathogen associated molecular patterns (PAMPS)in bacterial, fungi, virus and parasites. Human TLRs comprise a large family of 10 different type proteins that are expressed on various immune cells. Among these receptors, TLR1, 2, 4, 5, 6 and 10 were expressed on the cell surface. TLR2 form...

Evaluation of Soluble Toll-Like Receptors 2, 4, 9 and Their Damps Signaling Molecules (HMGB1 & HSP70) in Breast Cancer Patients of Basrah Province

Introduction: Toll-Like Receptors (TLRs) are members of pattern recognition receptors that recognize various molecules, including pathogen-associated molecular patterns and dead-associated molecular patterns. These receptors are expressed by immune, non-immune, and tumor cells. Some TLRs are implicated in tumor progression, while others are involved in tumor suppression. Our study aimed to eval...